How Science has Improved our Health
Thursdays, 9:30-11:30 A.M.
Instructor: Norm Curthoys
Course Objectives: The 70’s are the new 60’s!! This is largely due to advances in biochemistry and biotechnology that have increased our understanding of genetic disorders and of diseases such as diabetes, cancer, and elevated cholesterol. This knowledge formed the basis for the recent development of improved therapies. The course will discuss the advances in basic science that have lead to current understanding of the human genome. It will also discuss recent medical advances and the mechanisms by which new drugs and immunotherapies have resulted in improved outcomes in major diseases such as diabetes, cancer and heart disease.
Powerpoint Presentations (in pdf)
- Lecture 1A :DNA – A 4 letter code that determines our genetics.
- Lecture 1B: How DNA is sequenced and why it is important.
- Lecture 2A: Human Genome
- Lecture 2B: Genetic Defects and CRISPR
- Lecture 3A: Normal Metabolism
- Lecture 3B: Obesity
- Lecture 4A: Regulation of Glucose Metabolism
- Lecture 4B: Diabetes
- Lecture 5A: Cancer
- Lecture 5B: Cancer Metabolism
- Lecture 6A: Cancer Drug Therapy
- Lecture 6B: Cancer Immunotherapy
- Lecture 7A: Cholesterol
- DNA replication: https://youtu.be/TNKWgcFPHqw
- Ion Torrent Sequencing: https://youtu.be/WYBzbxIfuKs
- What are Haplogroups: https://youtu.be/eKCUSMBAI8I
Lecture 2 videos
- DNA to Protein: https://youtu.be/gG7uCskUOrA
- CRISPR-Cas9: https://youtu.be/2pp17E4E-O8
- Future of CRISPR: https://youtu.be/4YKFw2KZA5o
- Doudna TED Talk: https://youtu.be/TdBAHexVYzc
Supplemental Readings (in .pdf)